| Primary Identifier | MGI:5750546 | Allele Type | QTL |
| Gene | HrI1 | Inheritance Mode | Not Specified |
| Strain of Origin | WSB/EiJ | Is Recombinase | false |
| Is Wild Type | false |
| description | (A/J, C57BL/6J, 129S1/SvImJ, NOD/ShiLtJ and WSB/EiJ) affected the host response similarly and were associated with decreased influenza resistance (i.e. higher titers, higher weight loss, more pathology). NZO/HILtJ and PWK/PhJ alleles within the PreCC#/Unc population shared similar effects and increased influenza resistance. The authors report a novel CAST/EiJ allele in the Mx1 gene that confers limited protection from viral replication, but does protect from virus-induced weight loss. |
