| First Author | Czarneski J | Year | 2001 |
| Journal | J Virol | Volume | 75 |
| Issue | 23 | Pages | 11886-90 |
| PubMed ID | 11689671 | Mgi Jnum | J:73032 |
| Mgi Id | MGI:2154153 | Doi | 10.1128/JVI.75.23.11886-11890.2001 |
| Citation | Czarneski J, et al. (2001) Interleukin-4 Up-Regulates Mouse Mammary Tumor Virus Expression yet Is Not Required for In Vivo Virus Spread. J Virol 75(23):11886-90 |
| abstractText | The mouse mammary tumor virus (MMTV) superantigen induces T-cell production of cytokines, such as interleukin-4, which in turn increase MMTV transcription. However, interleukin-4 is not required for in vivo virus spread, because mice lacking interleukin-4 or the STAT6 transcription factor showed wild-type infection of lymphoid and mammary tissue. In spite of this, mammary tumor incidence was decreased in STAT6 null mice. |
