Primary Identifier | IPR039474 | Type | Domain |
Short Name | POMGNT1_PANDER-like |
description | O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) participates in O-mannosyl glycosylation and may be responsible for creating GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moieties on alpha dystroglycan and other O-mannosylated proteins [, ]. POMGnT1 consists of a stem domain, a catalytic domain, and an extended linker region connecting the two domains. The fold of the stem domain resembles that of PANDER (pancreatic-derived factor); a protein involved in the regulation of glucose homeostasis, but whose the molecular function has not been determined []. |