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Protein Domain : Cytoplasmic protein NCK1

Primary Identifier  IPR028526 Type  Family
Short Name  NCK1
description  Cytoplasmic protein NCK1 (NCK1) is a non-enzymatic adaptor protein composed of three SH3 (Src homology 3) domains and a C-terminal SH2 domain []. There aretwo vertebrate NCK proteins, NCK1 and NCK2.NCK1 mediates receptor tyrosine kinase signalling and modulates eIF2alphaSer51 phosphorylation by a subset of eIF2alpha kinases [, ]. NCK1 also mediates signalling from the ER membrane compartment [].

0 Child Features

1 Parent Features

7 Protein Domain Regions