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Allele : Notch4<tm1.1(cre/ERT2)Sat> notch 4; targeted mutation 1.1, Spyros Artavanis-Tsakonas

Primary Identifier  MGI:5304916 Allele Type  Targeted
Attribute String  Inducible, Recombinase Gene  Notch4
Transmission  Germline Strain of Origin  C57BL/6NTac
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  A targeting vector was constructed to insert the cre/ERT2 coding sequence, a polyadenylation signal and an Frt-flanked neo selection cassette in-frame with the start codon of Notch 4, by homologous recombination in ES cells. This resulted in deletion of most of exon 1. Chimeric males were bred to Flpe-expressing females to remove the selection cassette.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • N4-CreERT2<SAT>,
  • N4-CreERT2<SAT>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

1 Driven By

Trail: Allele

4 Publication categories

Trail: Allele