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Allele : Hpn<tm1Qwu> hepsin; targeted mutation 1, Qingyu Wu

Primary Identifier  MGI:3639336 Allele Type  Targeted
Attribute String  Null/knockout Gene  Hpn
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 5-8, which encode the conserved activation site and most of the catalytic domain, were deleted and replaced with a neomycin selection cassette. Northern blot analysis of total liver RNA derived from mutant mice demonstrated that no detectable transcript is expressed from this allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Tmprss1<->,
  • Tmprss1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories

Trail: Allele