Primary Identifier | MGI:3639336 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Hpn |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 5-8, which encode the conserved activation site and most of the catalytic domain, were deleted and replaced with a neomycin selection cassette. Northern blot analysis of total liver RNA derived from mutant mice demonstrated that no detectable transcript is expressed from this allele. |