First Author | Brockdorff N | Year | 1991 |
Journal | Genomics | Volume | 10 |
Issue | 1 | Pages | 17-22 |
PubMed ID | 1675191 | Mgi Jnum | J:11232 |
Mgi Id | MGI:59672 | Doi | 10.1016/0888-7543(91)90478-w |
Citation | Brockdorff N, et al. (1991) High-density molecular map of the central span of the mouse X chromosome. Genomics 10(1):17-22 |
abstractText | A total of 17 linking clones previously sublocalized to the central span of the mouse X chromosome have been ordered by detailed analysis through interspecific Mus spretus/Mus musculus domesticus backcross progeny. These probes have been positioned with respect to existing DNA markers utilizing a new interspecific backcross segregating for the Tabby (Ta) locus. The density of clones within this 11.5-cM interval is now, on average, one clone every 1000 kb. This high-density map provides probes in the vicinity of a number of important genetic loci in this region which include the X-inactivation center, the Ta locus, and the mottled (Mo) locus, and therefore provides a molecular framework for identification of the genes encoded at these loci. |