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Protein Domain : Leucine zipper putative tumour suppressor 1

Primary Identifier  IPR033293 Type  Family
Short Name  LZTS1
description  Leucine zipper putative tumor suppressor 1 (LZTS1, FEZ1) plays a role in mitosis []. It is associated with assembled microtubules and is involved in the stabilization of active p34CDC2 (Cdk1) []. LZTS1 plays an important role in ensuring proper Cdk1 activity during M phase. By maintaining high levels of Cdk1 activity, it prevents chromosomes missegregation []. LZTS1 plays an important role in human carcinogenesis [, , ].

0 Child Features

1 Parent Features

3 Protein Domain Regions