Primary Identifier | IPR033293 | Type | Family |
Short Name | LZTS1 |
description | Leucine zipper putative tumor suppressor 1 (LZTS1, FEZ1) plays a role in mitosis []. It is associated with assembled microtubules and is involved in the stabilization of active p34CDC2 (Cdk1) []. LZTS1 plays an important role in ensuring proper Cdk1 activity during M phase. By maintaining high levels of Cdk1 activity, it prevents chromosomes missegregation []. LZTS1 plays an important role in human carcinogenesis [, , ]. |