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Comment :

Type  MGI:General Description  after 14 days of osteogenic differentiation-inducing treatment, primary MEFs show no von Kossa or Alizarin Red staining, unlike wild-type MEFs; also, no increase in expression of the osteogenic transcription factor osterix and the matrix proteins osteocalcin and bone sialoprotein is observed, indicating impaired in vitro osteogenic differentiation