Primary Identifier | MGI:4418931 | Allele Type | Targeted |
Gene | Cebpb | Transmission | Germline |
Strain of Origin | 129P2/OlaHsd | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The coding sequence was replaced with a version with a mutant initiation site, ATG to TTG, followed by a floxed neo cassette. Cre mediated recombination removed the neo cassette. This change resulted in the absence of the 20 kDA isoform (LIP) encoded for by this locus but leaves expression of the larger isoforms intact. |