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Allele : Hand2<tm1Majh> heart and neural crest derivatives expressed 2; targeted mutation 1, Marthe J Howard
Primary Identifier  MGI:3804207 Allele Type  Targeted
Attribute String  Conditional ready, Hypomorph Gene  Hand2
Transmission  Germline Strain of Origin  129S1/SvImJ
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 1 and a floxed neo cassette was inserted downstream of exon 1. Quanitative RT-PCR analysis of jaws from E11 embryos indicated that transcript expression in homozygous embryos was only about 14% that of wild-type littermates. Therefore, this allele is a hypomorph.
  • mutations:
  • Insertion
  • synonyms:
  • Hand2<loxpneop>,
  • Hand2<flneo>,
  • Hand2<flneo>,
  • Hand2<loxpneop>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

6 Publication categories

Trail: Allele




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