|  Help  |  About  |  Contact Us

Protein Coding Gene : Adam24 ADAM metallopeptidase domain 24

Primary Identifier  MGI:105984 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  13526
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable integrin binding activity and metalloendopeptidase activity. Acts upstream of or within prevention of polyspermy. Located in external side of plasma membrane and sperm head plasma membrane. Is expressed in genitourinary system. Orthologous to human ADAM24P (ADAM metallopeptidase domain 24, pseudogene).
PHENOTYPE: Males homozygous for a targeted null mutation are subfertile and produce an increased number of polyspermic embryos at the pronuclear stage. Female homozygotes show normal fertility. [provided by MGI curators]
  • synonyms:
  • Adam24,
  • Dtgn5,
  • ADAM metallopeptidase domain 24,
  • disintegrin 5,
  • MGD-MRK-33664

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For