| Primary Identifier | MGI:6317366 | Allele Type | Targeted |
| Gene | Zdhhc5 | Transmission | Germline |
| Strain of Origin | C57BL/6N-A<tm1Brd> | Is Recombinase | false |
| Is Wild Type | false | Project Collection | EUCOMM |
| molecularNote | The L1L2_Bact_P cassette was inserted at position 84533249 of Chromosome 2 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre-mediated excision of the parental allele resulted in the removal of the promoter-driven neomycin selection cassette leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. |
