| Primary Identifier | MGI:2672795 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 259301 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to be involved in antimicrobial humoral immune response mediated by antimicrobial peptide and defense response to fungus. Predicted to act upstream of or within defense response to bacterium. Predicted to be located in extracellular region. Orthologous to human LEAP2 (liver enriched antimicrobial peptide 2). PHENOTYPE: Mice homozygous for a null allele sensitizes mice to acyl-ghrelin-induced loss of lean mass and obesity and female mice fed a high-fat diet exhibit increased body weight, increased food intake, increased body length, and increased hepatic liver steatosis, and lowered energy expenditure and locomotor activity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
