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Allele : Tg(TNNT2-deltaGlu160)15Imeg transgene insertion 15, Institute of Molecular Embryology and Genetics

Primary Identifier  MGI:3053202 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(TNNT2-deltaGlu160)15Imeg
Is Recombinase  false Is Wild Type  false
molecularNote  The transgene encodes a mutant human troponin T2, cardiac having a single-codon, in-frame deletion of the glutamic acid at amino acid position 160. This mutation was identified in affected members of families having dominantly inherited left ventricular hypertrophic cardiomyopathy which, although often mild or subclinical, is associated with a high incidence of sudden death at an early age.
  • mutations:
  • Insertion
  • synonyms:
  • TgN(cTnT delta Glu160)15Imeg,
  • TgN(cTnT delta Glu160)15Imeg
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele