| Primary Identifier | IPR040644 | Type | Domain |
| Short Name | HydF_tetramer |
| description | This entry represents the C-terminal domain of Hydrogen maturase F (HydF) from Thermotoga neapolitana. HydF is a GTPase that contains an FeS cluster-binding motif and is able to activate HydA production. This domain is known as domain III and is primarily responsible for homotetramer formation. Interactions between the two FeS cluster-binding domains are the interactions between the beta-2 strands, the initial part of the long loop that connects strand beta-2 to strand beta-3, and the loop that connects strand beta-1 to helix alpha-3. There are three highly conserved cysteine residues (Cys-302, Cys-353, and Cys-356) that represent the FeS cluster-binding site which form a superficial pocket []. |
