Primary Identifier | MGI:7408195 | Allele Type | Targeted |
Attribute String | Not Specified | Gene | Srsf2 |
Transmission | Germline | Strain of Origin | C57BL/6NTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting construct inserted a second coding region with a modified exon 1 containing the mutation (CCG to CAT) encoding the amino acid substitution proline with histidine at position 95 (P95H). The endogenous coding region was flanked with loxP and FRT sites. Cre-mediated recombination removed the coding region. |