Primary Identifier | MGI:5749788 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Camk2a-MAPT)601Ymot |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | An 8.5 kb portion of the calcium/calmodulin-dependent protein kinase II-alpha promoter containing upstream control regions and the transcriptional initiation site drives the expression of a human wild-type tau cDNA in forebrain neurons. Western blot confirmed expression in the brain and that tau becomes hyperphosphorylated with increasing age. |