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Protein Coding Gene : Tle2 transducin-like enhancer of split 2
Primary Identifier  MGI:104635 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  21886
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription and negative regulation of canonical Wnt signaling pathway. Predicted to act upstream of or within Wnt signaling pathway. Predicted to be located in focal adhesion and nuclear body. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; integumental system; limb; and sensory organ. Orthologous to human TLE2 (TLE family member 2, transcriptional corepressor).
  • synonyms:
  • MGD-MRK-26072,
  • transducin-like enhancer of split 2,
  • Grg2,
  • Tle2
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Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

1 Transgenic Expressors

Trail: ProteinCodingGene

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For





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