Primary Identifier | MGI:3512756 | Allele Type | Targeted |
Attribute String | Recombinase | Gene | Mapt |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | true | Is Wild Type | false |
molecularNote | An NLS-Cre-PGK-neo cassette was inserted into exon one, deleting most of the exon 1 coding sequence of the endogenous gene, shifting the start codon site 3 bp downstream and placing it in a partially optimized KOZAK consensus sequence. |