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Protein Coding Gene : Gcm1 glial cells missing homolog 1

Primary Identifier  MGI:108045 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  14531
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables DNA binding activity and zinc ion binding activity. Acts upstream of or within several processes, including astrocyte fate commitment; embryonic placenta development; and positive regulation of syncytium formation by plasma membrane fusion. Located in nucleus. Is expressed in several structures, including extraembryonic component; limb; metanephros; placenta; and thymus. Orthologous to human GCM1 (glial cells missing transcription factor 1).
PHENOTYPE: Homozygotes for targeted null mutations exhibit impaired branching of the chorioallantoic interface, absence of the placental labyrinth, lack of fusion of chorionic trophoblast cells, and lethality between embryonic days 5.5-10. [provided by MGI curators]
  • synonyms:
  • GCMa,
  • Gcm 1,
  • Gcm1-rs1,
  • Gcm a,
  • glial cell deficient,
  • glial cells missing homolog 1,
  • glide,
  • glial cells missing homolog (Drosophila), related sequence 1,
  • Gcm1,
  • MGD-MRK-37081

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For