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Publication : An atlas of mouse mammary gland development.

First Author  Richert MM Year  2000
Journal  J Mammary Gland Biol Neoplasia Volume  5
Issue  2 Pages  227-41
PubMed ID  11149575 Mgi Jnum  J:212824
Mgi Id  MGI:5582286 Doi  10.1023/a:1026499523505
Citation  Richert MM, et al. (2000) An atlas of mouse mammary gland development. J Mammary Gland Biol Neoplasia 5(2):227-41
abstractText  The mouse mammary gland is a complex tissue, which is continually undergoing changes in structure and function. Embryonically, the gland begins with invasion of the underlying fat pad by a rudimentary ductal structure. Postnatal growth occurs in two phases: ductal growth and early alveolar development during estrous cycles, and cycles of proliferation, differentiation, and death that occur with each pregnancy, lactation, and involution. The variety of epithelial structures and stromal changes throughout the life of a mammary gland makes it a challenge to study. The purpose of this histological review is to give a brief representation of the morphological changes that occur throughout the cycle of mouse mammary gland development so that developmental changes observed in mouse models of mammary development can be appreciated.
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