Primary Identifier | MGI:1860056 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Tnfrsf8 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A construct containing a neomycin resistance gene in the antisense direction was used to replace the second last (or second to last) exon. A dish binding assay indicated the absence of functional Tnfrsf8 protein on the surface of spleen cells isolated from homozygous mutant mice. |