| Primary Identifier | MGI:1919642 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 72392 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables potassium ion leak channel activity. Involved in lysosome organization; neuron cellular homeostasis; and potassium ion transmembrane transport. Predicted to be located in endosome membrane. Predicted to be active in endosome and lysosomal membrane. Orthologous to human TMEM175 (transmembrane protein 175). PHENOTYPE: Mice homozygous and heterozygous for a null allele exhibit dopaminergic neuron loss and impaired lysosomal K+ current in neurons. Heterozygotes also show impaired coordination. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
