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Allele : Pikfyve<Gt(AT0926)Wtsi> phosphoinositide kinase, FYVE type zinc finger containing; gene trap AT0926, Wellcome Trust Sanger Institute

Primary Identifier  MGI:3853063 Allele Type  Gene trapped
Attribute String  Null/knockout, Reporter Gene  Pikfyve
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
Project Collection  Sanger Inst. Gene Trap Res.
molecularNote  The gene trap vector inserted into intron 17. Quantitative real-time PCR detects both mutant and low levels of wild-type transcript in fibroblasts from homozygous mice. Western blot analysis detected low levels of protein in fibroblasts and multiple tissues from homozygous mice. The mutant protein fails to integrate into the Vac14 complex.
  • mutations:
  • Insertion of gene trap vector
  • synonyms:
  • Pikfyve<beta-geo>,
  • Pikfyve<beta-geo>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele