Primary Identifier | MGI:1917607 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 70357 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable calcium ion binding activity; potassium channel regulator activity; and transmembrane transporter binding activity. Predicted to be involved in positive regulation of action potential and regulation of potassium ion transmembrane transport. Predicted to act upstream of or within potassium ion transmembrane transport. Part of voltage-gated potassium channel complex. Is expressed in several structures, including brain; ganglia; intestine smooth muscle circular layer; spinal cord; and testis. Orthologous to human KCNIP1 (potassium voltage-gated channel interacting protein 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increase susceptibility to pentylenetetrazole-induced seizures. [provided by MGI curators] |