Primary Identifier | MGI:3522200 | Allele Type | Targeted |
Attribute String | Conditional ready, Modified regulatory region, No functional change | Gene | Rr185 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | This targeted mutation substitutes a 6-kilobase genomic DNA segment containing hs3b (Rr155) and hs4 (Rr156), the two most distant of four 3' transcriptional enhancers residing within the approximately 26 kb locus control region downstream of the Igh complex, with a loxP-flanked neomycin resistance gene cassette. |