| Primary Identifier | MGI:1927140 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 216963 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.4.0) Predicted to enable several functions, including GTPase activator activity; enzyme binding activity; and gamma-tubulin binding activity. Predicted to be a structural constituent of postsynaptic specialization. Involved in several processes, including cell redox homeostasis; modulation of chemical synaptic transmission; and nervous system development. Acts upstream of or within ephrin receptor signaling pathway. Located in postsynapse. Is active in calyx of Held. Is expressed in embryo. Used to study attention deficit hyperactivity disorder. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder. Orthologous to human GIT1 (GIT ArfGAP 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit postnatal lethality associated with abnormal lung vascular development with surviving mice exhibiting abnormal learning and anxiety related behavior. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
