| Type | MGI:General | Description | less than 15% of mice older than 6 months display spontaneous seizures mice are less sensitive to NMDA than wild-type LD50 values between 100-140 mg/kg, compared to 60-70 mg/kg for controls mice are more sensitive to kainic acid treatment than controls, exhibiting seizure activity at 28 mg/kg vs 32 mg/kg in controls with 43% mortality |
