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Protein Coding Gene : Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10
Primary Identifier  MGI:88611 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  13117
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable monooxygenase activity. Predicted to be involved in fatty acid metabolic process; icosanoid biosynthetic process; and kidney development. Predicted to act upstream of or within lipid metabolic process. Located in intracellular membrane-bounded organelle. Is expressed in liver and urinary system. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human CYP4A11 (cytochrome P450 family 4 subfamily A member 11).
PHENOTYPE: Mice homozygous for a null mutation display salt-sensitive hypertension, decrease sodium excretion, and decreased urine output. [provided by MGI curators]
  • synonyms:
  • cytochrome P450, 4a,
  • MGD-MRK-6982,
  • MGD-MRK-14013,
  • D4Rp1,
  • MGD-MRK-2333,
  • MGD-MRK-2334,
  • RP1,
  • Msp-3,
  • Cyp4a10,
  • DNA segment, Chr 4, Roswell Park 1,
  • Roswell Park 1, DNA polymorphism,
  • cytochrome P450, family 4, subfamily a, polypeptide 10,
  • Cyp4a,
  • expressed sequence AI647584,
  • MGI:2140347,
  • AI647584
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4 Involved In Mutations

Trail: ProteinCodingGene

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11 Pathways

Trail: ProteinCodingGene

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