|  Help  |  About  |  Contact Us

Protein Coding Gene : Kif2a kinesin family member 2A

Primary Identifier  MGI:108390 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  16563
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0)

Predicted to enable several functions, including ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in dendritic transport. Located in sperm principal piece. Is active in GABA-ergic synapse. Is expressed in central nervous system and dorsal root ganglion. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 3. Orthologous to human KIF2A (kinesin family member 2A).
PHENOTYPE: Homozygous null mice display neonatal lethality, abnormal lamination of the cerebral cortex, hippocampus and cerebellum, impaired neuronal migration, and abnormal axon outgrowth. [provided by MGI curators]
  • synonyms:
  • M-kinesin,
  • Kns2,
  • MGD-MRK-11591,
  • kinesin family member 2,
  • MGD-MRK-37430,
  • Kif2,
  • kinesin family member 2A,
  • Kif2a

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

29 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For