First Author | Yeung RS | Year | 1994 |
Journal | Curr Opin Immunol | Volume | 6 |
Issue | 2 | Pages | 298-307 |
PubMed ID | 8011213 | Mgi Jnum | J:17598 |
Mgi Id | MGI:65632 | Doi | 10.1016/0952-7915(94)90105-8 |
Citation | Yeung RS, et al. (1994) T-cell development and function in gene-knockout mice. Curr Opin Immunol 6(2):298-307 |
abstractText | The use of mice with defined genetic defects engineered by homologous recombination in embryonic stem cells has greatly enhanced our understanding of immune functions at the single-gene level. The complex molecular interactions involved in T-cell development and antigen recognition have been especially targeted for detailed analysis via knockout technology. |