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Protein Coding Gene : Ptgfr prostaglandin F receptor

Primary Identifier  MGI:97796 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  19220
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable prostaglandin F receptor activity. Involved in positive regulation of gene expression and response to estradiol. Acts upstream of or within negative regulation of apoptotic process and response to lipopolysaccharide. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Is expressed in cloaca; genital tubercle; jaw; and viscerocranium. Orthologous to human PTGFR (prostaglandin F receptor).
PHENOTYPE: Pregnant females homozygous for a targeted null mutation are unable to deliver their offspring due to lack of induction of the oxytocin receptor and fail to show the normal decline of serum progesterone levels preceding parturition. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI957154,
  • PGF,
  • MGI:2139843,
  • Ptgfr,
  • prostaglandin F receptor,
  • MGD-MRK-13663,
  • FP,
  • AI957154

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For