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Allele : Dmpk<tm2Bew> dystrophia myotonica-protein kinase; targeted mutation 2, Be Wieringa

Primary Identifier  MGI:3665271 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Dmpk
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 13-15 were replaced with the human coding sequence for a long CTG84 repeat. Northern blot analyses demonstrated that mutant mice expressed the predicted chimeric mouse-human transcripts, resulting from alternative splicing of mouse 12 to either human exon 14 or 15.
  • mutations:
  • Insertion
  • synonyms:
  • DM1 (CTG)n.(CAG)n,
  • DM1 (CTG)n.(CAG)n
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories