Primary Identifier | MGI:3665271 | Allele Type | Targeted |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Dmpk |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 13-15 were replaced with the human coding sequence for a long CTG84 repeat. Northern blot analyses demonstrated that mutant mice expressed the predicted chimeric mouse-human transcripts, resulting from alternative splicing of mouse 12 to either human exon 14 or 15. |