| First Author | Aida K | Year | 1993 |
| Journal | Biochim Biophys Acta | Volume | 1174 |
| Issue | 1 | Pages | 72-4 |
| PubMed ID | 7916639 | Mgi Jnum | J:13160 |
| Mgi Id | MGI:61368 | Doi | 10.1016/0167-4781(93)90093-s |
| Citation | Aida K, et al. (1993) Cloning and nucleotide sequence of a novel, male-predominant carboxylesterase in mouse liver. Biochim Biophys Acta 1174(1):72-4 |
| abstractText | As a family of serine-dependent enzymes, the carboxylesterases (EC 3.1.1.1) demonstrate a broad substrate specificity. Mouse carboxylesterases comprise at least 20 genetically distinct loci. We cloned a full-length cDNA for a novel mouse carboxylesterase, Es-male which was expressed predominantly in male livers. This carboxylesterase consisted of 554 amino acid residues, and exhibited 43% and 42% similarities to the known mouse esterases Es-22 and pEs-N, respectively. Es-male contained a C-terminal ER-retention signal PEEL, indicating that it may be a microsomal carboxylesterase. |
