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Protein Domain : Tenascin-R

Primary Identifier  IPR033079 Type  Family
Short Name  TNR
description  Tenascin-R (TNR) is an extracellular matrix glycoprotein that is expressed primarily in the central nervous system. It regulates neurogenesis and affects cell migration, adhesion and differentiation [, ].Tenascins are extracellular matrix glycoproteins that act both as integrin ligands and as modifiers of fibronectin-integrin interactions toregulate cell adhesion, migration, proliferation and differentiation. Tenascins are usually composed of repeated epidermal growth factor (EGF)-like domains, fibronectin-type III (FNIII) domains and a C-terminal fibrinogen related domain (FReD) [].

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5 Protein Domain Regions