| First Author | Engel DA | Year | 1988 |
| Journal | Virology | Volume | 166 |
| Issue | 1 | Pages | 24-9 |
| PubMed ID | 2457983 | Mgi Jnum | J:9335 |
| Mgi Id | MGI:57797 | Doi | 10.1016/0042-6822(88)90142-0 |
| Citation | Engel DA, et al. (1988) Interferons as gene activators: close linkage of two interferon-activatable murine genes. Virology 166(1):24-9 |
| abstractText | Previously we have identified a mouse genomic clone (clone 5) which specifies the 5' flanking region and the 5' terminal exon of an interferon-activatable gene (202 gene). Here, we show that about 5 kb upstream from this flanking region in clone 5 there occurs a 3' terminal region of a second interferon-activatable gene (203 gene). The two genes are transcribed in the same direction. Segments from the 203 gene can be hybridized to a set of five interferon-inducible RNAs. The 203 mRNAs are induced about 15-fold in interferon-treated Ehrlich ascites tumor cells. |
