| First Author | Yanagimoto T | Year | 1992 |
| Journal | Biochim Biophys Acta | Volume | 1130 |
| Issue | 3 | Pages | 329-32 |
| PubMed ID | 1339292 | Mgi Jnum | J:529 |
| Mgi Id | MGI:49066 | Doi | 10.1016/0167-4781(92)90447-8 |
| Citation | Yanagimoto T, et al. (1992) Mouse liver cytochrome P-450 (P-450IIIAM1): its cDNA cloning and inducibility by dexamethasone. Biochim Biophys Acta 1130(3):329-32 |
| abstractText | A full-length cDNA complementary to mouse liver mRNA coding for one of the cytochromes P-450 (P-450) in the P-450IIIA family, namely P-450IIIM1, was isolated and completely sequenced. The sequence of this cDNA clone, pMDex13, revealed that it encoded a polypeptide of 504 deduced amino acid residues (Mr = 57,853). The deduced amino acid sequence showed 87.3 and 84.9% identity with rat P-450IIIA1 and P-450IIIA2, respectively. The NH2-terminal 24 amino acid sequences of P-450IIIAM1 were completely identical with purified mouse P-450UT protein. RNA blot analysis showed that mRNA content of hepatic P-450IIIAM1 was remarkably increased by treatment of mice with dexamethasone. |
