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Allele : Ace<tm8Keb> angiotensin I converting enzyme; targeted mutation 8, Kenneth E Bernstein

Primary Identifier  MGI:4830150 Allele Type  Targeted
Gene  Ace Transmission  Germline
Strain of Origin  129 Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 20 was replaced with one in which nucleotide substitutions result in the amino acid substitutions of lysines for histidines at positions 993 and 997 (H993K and H997K). A floxed neo cassette was inserted upstream of the modified exon. The absence of protein expression was confirmed by western blot analysis.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • ACE12,
  • ACE12
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele