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Allele : Ift140<tm1b(KOMP)Wtsi> intraflagellar transport 140; targeted mutation 1b, Wellcome Trust Sanger Institute

Primary Identifier  MGI:5311831 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Ift140
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
Project Collection  KOMP-CSD
molecularNote  The L1L2_Bact_P cassette was inserted at position 25168608 of Chromosome 17 upstream of the critical exon(s) (Build 37). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 7 at position 25169359. Exon 7 is thus flanked by loxP sites. Cre expression excised exon 7 and the neomycin selection cassette resulting in the creation of a reporter knockout mouse.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Ift140<null1>,
  • Ift140<null1>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

9 Publication categories

Trail: Allele