Primary Identifier | MGI:5311831 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Ift140 |
Transmission | Germline | Strain of Origin | C57BL/6N |
Is Recombinase | false | Is Wild Type | false |
Project Collection | KOMP-CSD |
molecularNote | The L1L2_Bact_P cassette was inserted at position 25168608 of Chromosome 17 upstream of the critical exon(s) (Build 37). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 7 at position 25169359. Exon 7 is thus flanked by loxP sites. Cre expression excised exon 7 and the neomycin selection cassette resulting in the creation of a reporter knockout mouse. |