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Protein Coding Gene : Nadk2 NAD kinase 2, mitochondrial

Primary Identifier  MGI:1915896 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  68646
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable NAD+ kinase activity and protein homodimerization activity. Predicted to be involved in NAD metabolic process. Located in mitochondrion. Is expressed in retina. Orthologous to human NADK2 (NAD kinase 2, mitochondrial).
PHENOTYPE: Mice homozygous for knock-out allele exhibit increased serum lysine and carnitine levels, develop increased reactive oxygen species levels and hepatic steatosis on an atherogenic high-fat diet, and show impaired fasting-induced fatty acid oxidation. [provided by MGI curators]
  • synonyms:
  • MGI:1918451,
  • Nadk2,
  • Nadkd1,
  • RIKEN cDNA 1110020G09 gene,
  • NAD kinase 2, mitochondrial,
  • 4933430B08Rik,
  • NAD kinase domain containing 1,
  • 1110020G09Rik,
  • RIKEN cDNA 4933430B08 gene,
  • MNADK

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Genome

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0 Canonical

0 CDSs

0 Exons

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0 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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