Primary Identifier | MGI:3053093 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Nobox |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector was designed to replace part of exon 2 and all of exons 3-8, encoding the homeodomain and including the polyadenylation signal, with a Pgk1-HPRT cassette. Southern blot and multiplex PCR confirmed recombination in mice. |