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Allele : F2rl1<em2Wmrf> F2R like trypsin receptor 1; endonuclease-mediated mutation 2, Wolfram Ruf
Primary Identifier  MGI:7434623 Allele Type  Endonuclease-mediated
Gene  F2rl1 Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  Serine codon 365 (AGT) and threonine codon 368 (ACT) in exon 2 were changed to alanine (GCG) (p.S365A, p.T368A) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutations block phosphorylation of the residues in the encoded peptide.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • PAR2 S365A/T368A,
  • PAR2 S365A/T368A,
  • F2rl1<em2Ruf>,
  • F2rl1<em2Ruf>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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