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Allele : Tg(Or10j5-Or6a2*,-EYFP)1Hsak transgene insertion 1, Hitoshi Sakano

Primary Identifier  MGI:3766291 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Or10j5-Or6a2*,-EYFP)1Hsak
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene puts the rat Olfr2 gene under the control of the mouse Olfr16 promoter. In the rat Olfr2 gene, the DRY motif at the cytoplasmic end of the transmembrane domain III was mutated to RDY. It was predicted this mutation would prevent association of G proteins involved in downstream signaling. An enhanced yellow fluorescent protein (YFP) reporter gene was also inserted downstream of the rat gene. YFP expression is observed in zone 1 of the olfactory epithelium of transgenic mice.
  • mutations:
  • Insertion
  • synonyms:
  • 17(RDY)-IRES-EYFP,
  • Tg(Olfr16-Olfr2*,-YFP)1Hsak,
  • 17(RDY)-IRES-EYFP,
  • I7-RDY-IRES-YFP,
  • I7(RDY),
  • I7-RDY-IRES-YFP,
  • I7(RDY),
  • Tg(Olfr16-Olfr2*,-YFP)1Hsak
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

8 Publication categories

Trail: Allele