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Protein Coding Gene : Rbbp6 retinoblastoma binding protein 6, ubiquitin ligase

Primary Identifier  MGI:894835 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  19647
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable protein kinase binding activity and ubiquitin protein ligase activity. Involved in ubiquitin-dependent protein catabolic process. Acts upstream of or within embryonic organ development; in utero embryonic development; and somite development. Predicted to be located in nuclear speck. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Predicted to colocalize with centrosome. Is expressed in left lung and right lung. Orthologous to human RBBP6 (RB binding protein 6, ubiquitin ligase).
PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality, reduced size, growth retardation and increased apoptosis. [provided by MGI curators]
  • synonyms:
  • MGI:2142318,
  • C77662,
  • MGI:1344330,
  • expressed sequence C77662,
  • RIKEN cDNA C030034J04 gene,
  • C030034J04Rik,
  • RIKEN cDNA 4933422O15 gene,
  • expressed sequence AI316869,
  • BB233631,
  • MGI:2142301,
  • Rbbp6,
  • 4933422O15Rik,
  • expressed sequence BB233631,
  • retinoblastoma binding protein 6, ubiquitin ligase,
  • MGI:1921709,
  • MGI:2141903,
  • MGI:1924749,
  • AI316869

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