| Primary Identifier | MGI:2677369 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Sirt1 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A single loxP site remained in place of exons 5, 6, and 7 after the floxed neo cassette inserted by homologous recombination was excised via in vitro cre-mediated recombination. Protein was undetected in homozygous mutant MEFs by Western blot analysis using an antibody specific for the N-terminal. |
