Primary Identifier | MGI:3603530 | Allele Type | Chemically induced (ENU) |
Gene | Frem2 | Inheritance Mode | Recessive |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | These mutants have a C to A transversion that generates a stop codon and produces a truncated protein of 1,880 amino acids out of the normal 3,100, and lacking four of the five CALXbeta motifs. If a truncated protein would be produced, the loss of several conserved regions suggests that nay product would have limited function. |