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Publication : Differential expression of fos and jun family members during murine postnatal intestinal development.

First Author  Blais S Year  1996
Journal  Biol Neonate Volume  69
Issue  5 Pages  342-9
PubMed ID  8790912 Mgi Jnum  J:34220
Mgi Id  MGI:81686 Doi  10.1159/000244328
Citation  Blais S, et al. (1996) Differential expression of fos and jun family members during murine postnatal intestinal development. Biol Neonate 69(5):342-9
abstractText  We have examined the patterns of expression of members of the fos and jun families of transcription factors during murine postnatal intestinal development. Northern analysis showed increases in fosB, c-fos, and junB mRNA levels in both proximal jejunum and colon. These increases coincide with weaning a period of major changes in intestinal cell proliferation and migration. Administration of dexamethasone to suckling mice resulted in transient induction of c-fos mRNA levels in all gut segments. Thus, modifications in expression of certain members of the fos and jun families in vivo correlate with major maturational changes during murine intestinal development and support a role for these transcription factors in the regulation of intestinal functions.
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