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Protein Coding Gene : Zmynd8 zinc finger, MYND-type containing 8

Primary Identifier  MGI:1918025 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  228880
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable several functions, including histone binding activity; transcription corepressor activity; and zinc ion binding activity. Predicted to be involved in several processes, including positive regulation of filopodium assembly; regulation of postsynapse organization; and regulation of transcription by RNA polymerase II. Predicted to be located in dendrite; nuclear lumen; and site of DNA damage. Predicted to be part of chromatin. Predicted to be active in cytoplasm and nucleus. Is expressed in central nervous system; early conceptus; female reproductive system; and urinary system. Orthologous to human ZMYND8 (zinc finger MYND-type containing 8).
PHENOTYPE: Mice homozygous for a conditional allele activated in mammary tissue exhibit reduced mammary tumors and abolished lung metastasis in a transgenic breast cancer model. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 3632413B07 gene,
  • RIKEN cDNA 1110013E22 gene,
  • 1110013E22Rik,
  • MGI:2138895,
  • AL024039,
  • 3632413B07Rik,
  • RIKEN cDNA 2010005I16 gene,
  • RACK7,
  • MGI:2139133,
  • Zmynd8,
  • 2010005I16Rik,
  • expressed sequence AI316811,
  • mKIAA1125,
  • expressed sequence AL024039,
  • AI316811,
  • ZMYND8,
  • MGI:1920968,
  • protein kinase C binding protein 1,
  • Prkcbp1,
  • zinc finger, MYND-type containing 8,
  • MGI:1917081

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