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Allele : Srd5a1<tm1Mahe> steroid 5 alpha-reductase 1; targeted mutation 1, Mala Mahendroo

Primary Identifier  MGI:1857454 Allele Type  Targeted
Attribute String  Null/knockout Gene  Srd5a1
Transmission  Germline Strain of Origin  129S7/SvEvBrd
Is Recombinase  false Is Wild Type  false
molecularNote  A region encompassing promoter region and the a 3' portion of exon 1, encoding thr first 36 amino acids, was replaced by a neomycin selection cassette. Northern blot analysis of total RNA isolated from several organs showed an absence of transcript in homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Srd5a1<->,
  • 5alphaRKO,
  • Srd5a1<->,
  • 5alphaRKO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

22 Publication categories

Trail: Allele